This paper presents a simulation-based analysis of local mitigation strategies for managing material procurement risks in manufacturing environments. Focusing on factory-level mitigation strategies, the study investigates how different types of procurement-related disruptions affect production efficiency and identifies and evaluates mitigation strategies - such as safety stock adjustments, procurement volume control and variable processing - that enhance resilience and sustainability. Two archetypal production layouts are considered: a linear assembly line and a non-linear fractal configuration. By systematically modelling risk scenarios across these layouts, the study evaluates the effectiveness of individual and combined strategies in maintaining stable and efficient production. The results highlight key interdependencies between risk type, factory layout and mitigation approach, offering actionable insights for production planners. The analysis reveals that the effectiveness of mitigation strategies strongly depends on the production layout, with flexible configurations showing significantly greater potential to absorb disruptions. Linear systems, by contrast, exhibit more limited adaptability, reinforcing the need for layout-sensitive resilience planning. These findings support the development of adaptive, locally resilient manufacturing systems capable of responding to supply volatility while contributing to broader sustainability objectives.