This chapter introduces triple integrals as a powerful mathematical tool for analyzing functions of three variables within solid three-dimensional regions. Expanding upon the concepts of single and double integration, triple integrals allow for the calculation of complex physical quantities such as volume, mass, and moments for objects distributed in space. The text provides a detailed review of essential single-variable integration rules before transitioning into the evaluation of iterated integrals. Key topics include the strategic selection of the order of integration to simplify calculations and the application of cylindrical and spherical coordinate systems for problems involving radial or axial symmetry. Furthermore, the chapter demonstrates how to utilize MATLAB for both symbolic and numerical triple integration, providing a modern computational approach to solving spatial problems.