This chapter investigates the function of cultural programming as a driving force for sustainability and social cohesion in depopulated rural areas of Spain, with particular emphasis on Fuendetodos (Zaragoza), the birthplace of Goya. Drawing upon the concept of “Empty Spain” and its evolution towards the “rural turn,” the study illustrates how certain small communities are implementing cultural initiatives that enhance heritage value, promote community engagement, and attract visitors, thereby strengthening the local economy. In Fuendetodos, cultural institutions such as Casa de Goya, Museo del Grabado, or Goya Street Art Museum have been established alongside events like the Fiesta Goyesca, which integrate art, history, and sustainability. The active involvement of the local community has been essential in fostering identity and resilience. Furthermore, attention to natural heritage is evident through initiatives such as the Fuendeverde center. The article also proposes strategies to incorporate these heritage assets across all educational levels to encourage interdisciplinary learning in history, art, geography, and sustainability. Finally, it underscores the necessity for institutional support and effective communication strategies to establish Fuendetodos as a model of rural revitalization that harmonizes memory, culture, and future development within the framework of the Sustainable Development Goals.