This work is aimed at providing current nanotechnology students and academics with a state-of-the-art review of how to navigate this exciting and novel career path in nanotechnology considering their general curricula and location. The significance of this new career is driven by the upcoming industrialized applications that require the incorporation of nanotechnological expertise. However, national economical investment from each country is always a limiting factor for the grow of nanotechnology when compared to non-Latin American countries. The amount of nanotechnology specialists required worldwide is expected to be over 2 million people by 2024, making the field of Nanotechnology one of the most versatile, interdisciplinary, and attractive careers nowadays. In this work we will demonstrate that a student who has completed Nanotechnology Engineering in Latin America is able to adapt to academic or industry settings according to their chosen career path. However, there is an inherent need for professionalization that has not been realized in the majority of universities, increasing the importance of pursuing a master’s degree to meet the demands of both academic and industrial fields. In this work the importance for course selection in Physics, Chemistry or Biology, as well as the required investment are addressed. In this sense, fundamental aspects that are crucial for improving the academic and professional perspectives of Latin American students seeking nanotechnology careers are identified and discussed as providing a state of the art perspective compared to international needs. This work provides a guide for students and professionals who are about to enter the highly competitive interdisciplinary field of nanotechnology.