In the current fast-paced and emotionally charged healthcare environment, married female nurses often have to cope with two major duties at the same time: the high-intensity workload of patient care and the daily routine of looking after their families. This steady overlap gives rise to substantial work-life balance (WLB) challenges, which in turn have an impact on stress levels, emotional well-being, and job performance. The study attempts to find out the degree of work-life imbalance among married female nurses in the healthcare sector and to what extent factors like work hours, household support, and caregiving duties influence their experiences. A quantitative research method was used, in which a structured questionnaire was given to 101 married female nurses for data collection. The statistical analyses—Chi-square tests, Spearman's rank correlation, and the Mann-Whitney U test—revealed significant relationships between long working hours and increased difficulty in managing work and home duties. The limited household support and the extra caregiving responsibilities were also associated with markedly higher stress levels. In addition, the rigid schedules and lack of supportive institutional policies intensified these problems. The study emphasizes the necessity for workplace policies that are not only culturally sensitive but also supportive to nurses’ well-being and the overall quality of healthcare services.