Diaphyseal clavicle fractures are common in the pediatric and adolescent population, with the diaphyseal region accounting for approximately 90% of clavicle fractures, followed by the lateral third (10–15%) and medial third fractures (0–5%) (Nordqvist and Petersson. Clin Orthop Relat Res 300, 1994; van der Meijden et al. J Shoulder Elb Surg 21(3), 2012; Landin LA. Acta Orthop 54(S202), 1983; Mukhtar et al. J Child Orthop 12(2), 2018). Due to the open physes and thick periosteum, children’s clavicle fractures demonstrate fantastic healing potential. As a result, most pediatric clavicle fractures are managed nonoperatively, with low rates of nonunion (< 1%) and symptomatic malunion (< 2%) (Jasty and Heyworth. J Pediatr Orthop Soc North Am 2(3) 2020; Heyworth et al. Am J Sports Med 50(11):3045–3055, 2022). The current chapter outlines strategies to optimize outcomes, minimize costs, and enhance value when treating pediatric diaphyseal clavicle fractures.