The emergence of virtual realities introduces dynamics of transformation and morphogenetic modeling. They are based on dialogic computational processes, articulating myths, architectural and archaeological data, which we designate by the concept of “virtuo-morphosis.” This article explores this new hermeneutic process enabling the morphological interpretation of architectural elements in relation to their mythogenesis, within a generative framework assisted by artificial intelligence (AI). The methodology is based on a multi-instance computational approach, structured in four stages: (1) the articulation of transdisciplinary data; (2) morpho-structural analysis; (3) the creation of a mytho-symbolic database derived from a structuralist reading of the myths; (4) the encoding of this database in the form of prompts guiding the AI-assisted transformation. The case study focuses on the mythogenesis of the Corinthian capital as described by Vitruvius, analyzed as an experimental simulation model. By implementing a morpho-symbolic framework applied to virtual forms, the results allow for the identification of symbolic, morphological, and semiotic differences and enrichments, ensuring an understanding of the ontology of the original forms. The study highlighted the role of myth as a cognitive and systemic matrix, guiding AI in the transformation and symbolic re-actualization of architectural elements, thus opening up renewed cultural and educational perspectives.