A Deep Learning Framework for Detecting Multiple Eye Disorders in Retinal Fundus Photography
摘要
Early and accurate detection of eye diseases is crucial for preventing vision loss and enabling early treatment. Retinal fundus photography plays a vital role in this, as it offers a convenient, non-invasive, and cost-effective method to examine the innermost surface of the eye. While useful as external diagnostic references, manual interpretation of fundus images is often time-consuming, subjective, and inconsistent. To address these challenges, this study proposes a deep learning-based method for classifying retinal fundus images into cases of diabetic retinopathy (DR), glaucoma, cataract, age-related macular degeneration (AMD), and normal. We compare four popular CNN models a base CNN, ResNet50, DenseNet121, and EfficientNet-B3 trained and validated on a curated dataset of labeled images using common pre-processing and augmentation techniques. Model performance is assessed using accuracy, precision, recall, F1-score, AUC, confusion matrices, and disease-specific analyses. The results show that transfer learning methods, particularly EfficientNet-B3, outperform the baseline CNN. Our findings suggest that deep learning has the potential to enhance retinal analysis across multiple diseases, assist ophthalmologists, and reduce their workload by enabling large-scale screening for early detection of sight-threatening conditions.