In an era marked by global disruptions, environmental challenges, and heightened stakeholder expectations, supply chain resilience has emerged as a critical competency for B2B firms striving for long-term sustainability. This paper investigates the adaptive strategies employed by B2B firms to enhance supply chain resilience while aligning with sustainable development goals. Through an integrated framework combining risk mitigation, digital transformation, and circular economy principles, we explore how companies anticipate, absorb, and recover from disruptions. Drawing on empirical analysis and industry case studies, the research highlights the role of agility, collaboration, and technological innovation in creating resilient yet environmentally conscious supply chains. The findings underscore that sustainability and resilience are not mutually exclusive but mutually reinforcing objectives. The study offers strategic insights for decision-makers aiming to future-proof their supply chains against uncertainty while maintaining ecological integrity and economic competitiveness.