With the rapid development of Yangtze River channel construction, the comprehensive benefits of channel regulation structures have become increasingly prominent. Accurately evaluating the technical condition of completed channel regulation structures, ensuring they fully exert their channel regulation functions, and improving channel conditions are important tasks in channel maintenance and management. This paper takes the channel regulation structures from Jiangyin to Liuhe in the Yangtze River as the research object, and comprehensively adopts various technical methods such as unmanned aerial vehicle (UAV) aerial survey, correlation analysis between recent river regime changes and channel evolution, and quantitative analysis of the degree of damage to structures to carry out technical condition evaluation research. The research indicates that the technical condition of the evaluated channel regulation structures is generally good. In the later stage, attention should be paid to the stability of prefabricated components of the Langshan sand submerged breakwater in Tongzhousha channel and the integrity of T8 spur dike. The research results provide key technical support for the maintenance and management of channel regulation structures.