In today’s globalized and digitalized world, intercultural communication and media literacy are essential competencies for professionals across all fields. HTW Dresden, a leading university of applied sciences in Germany, addresses this need through its innovative Intercultural Communication module. Designed to equip students with cultural sensitivity, self-awareness, and critical media consumption skills, the module combines theoretical foundations with practical applications such as role-playing, simulations, and portfolio-based assessments. This paper explores the structure, methodology, and outcomes of the module, emphasizing its interdisciplinary relevance and transformative impact on students. A portfolio analysis conducted with 23 participants from diverse faculties highlights significant improvements in self-perception, intercultural engagement, and the ability to critically evaluate media. The findings underscore the module’s success in fostering intercultural competencies and its adaptability for implementation at other institutions, including Hochschule Zittau/Görlitz. By integrating intercultural communication into its curriculum, HTW Dresden prepares graduates to navigate the complexities of global collaboration and misinformation in the digital age. This analysis positions the module as a model for interdisciplinary education, offering a framework for embedding cultural awareness and media literacy into higher education to meet the demands of an interconnected world.