This study presents the design and analysis of a novel solar-based multi-generation system integrating concentrating solar power (CSP), gas turbine cycle, steam Rankine cycle (SRC), heat pump, and proton exchange membrane electrolyzer (PEME) for simultaneous electricity, heating, and green hydrogen production. The system was evaluated across multiple Italian sites to capture diverse solar potentials, using detailed energy, exergy and dynamic analysis under real operating conditions. Results show Rome achieved the highest combined energy and exergy efficiencies, reaching 24.68% and 18.52% in August, outperforming sites like Trieste and Genova. Cagliari recorded the highest green hydrogen production rates-76.82 kg/h in June, 80.50 kg/h in July, and 70.52 kg/h in August-making it the best location for hydrogen generation despite slightly lower efficiencies. In July, the system in Cagliari demonstrated an energy efficiency of 24.5%, producing 10,470 kW electricity and 6,779 kW heating, with an exergy efficiency of 18.34% and hydrogen output of 80.5 kg/h. Exergy destruction was dominated by the CSP subsystem (83.8%), followed by PEME (5.7%), while SRC and heat pump subsystems contributed minimally. The heliostat and receiver had the highest exergy destruction rates (26,937 kW and 18,271 kW), whereas the condenser, pump, and HEX2 had the lowest. Gas turbine and evaporator achieved the highest exergy efficiencies (94.82% and 93.4%), while PEME and air heater showed lower efficiencies (42.66% and 43.76%). These findings highlight the system’s potential for efficient multi-generation and guide optimal site selection for green hydrogen production in Italy.