Starting from the basics of ergonomics of the work process, man and machine interaction, through the specifics of the ergonomics of the cockpit of a modern supersonic fighter aircraft, the paper analyzes the impact of acceleration, especially positive G force on a pilot's work process. Empirical data are also presented, which show the effects of different forces on the pilot's working abilities, as well as the impact of the human factor on the modeling of the ergonomics of the modern cockpit, the workplace of a fighter pilot. The concept of cockpit ergonomics involves a wide range of details that are considered during prototype development. However, in this paper, the focus is on the ergonomics of the ejection seat placed in combat aircraft, based on the pilot's G tolerance during aircraft maneuvering. Finally, the paper defines measures for controlling and reducing the negative consequences of exposing pilots to high G force even above 10G, applying a methodology that has been confirmed in practice on various combat aircraft of Western and Eastern manufacturers.