This study presents a large-scale empirical analysis of DNSover-Encryption (DoE) protocols, focusing on the adoption, protocol feature support, and impact on webpage loading performance. We conducted measurements across over three thousand DoE resolvers, characterizing their support for features such as session resumption and 0-Round-trip Time (RTT) in DNS-over-QUIC (DoQ) and DNS-over-HTTP/3 (DoH/3). Despite broader feature adoption by DoQ, major browsers currently favor DoH/3. Our extensive latency measurements demonstrate that both protocols perform comparably, with DoQ slightly outperforming on average. Complementary experiments with the top one million websites show negligible overall page load time penalties when using DoQ or DoH/3 compared to traditional DNS-over-UDP (Do53), even under low-latency conditions. Further, our analysis explores the relationship between webpage complexity, quantified via metrics including number of objects, queried servers, and MIME type diversity, and the performance impact of DoE. We find no statistically significant correlation, indicating that DoEs performance effects are consistent across a range of website architectures. The study also addresses limitations in current client support for key protocol enhancements and validates effective 0-0-RTT resumption using proxy resolvers. Our findings alleviate prevalent concerns about DoE-induced performance degradation, supporting broader adoption of encrypted Domain Name System (DNS) protocols without sacrificing user experience. We release our datasets, source code, and analysis scripts to facilitate reproducibility and foster further research into encrypted DNS ecosystems.