Post-traumatic stress disorder (PTSD) and stress-related disorders are highly prevalent in the general population. However, women have a higher prevalence of these disorders and a higher risk of developing PTSD following a traumatic event. Although the reasons for this are likely to be both social and biological, the fact that they are exposed to a greater number of interpersonal traumas from childhood influences the development of the disorder. When treating PTSD, it is necessary to consider the influence of gender: gender-based violence must be recognized as a systemic phenomenon that not only affects at an individual level. Given the universal and systemic nature of violence against women, many women presenting for treatment have experienced this violence at some point in their lives. While treatment for traumatic exposure is necessary and has been shown to be effective, there is also a need to promote the empowerment and dignity of discriminated groups, such as women and non-binary individuals, who may be particularly distrustful of the health care system due to previous experiences of discrimination. In addition, many of these patients will also require psychosocial support, so a multidisciplinary approach is needed to introduce the gender perspective in trauma care.