Anna Meyer, an otolaryngologist, is not sure exactly when the change came. Her mother spoke often of the spiritual signposts in her own life and she, the daughter, clung to science and ignored the ether. In her story, she recalls how in retrospect, she can see that it was not one moment, but an accumulation, a gathering around her. In this essay, Meyer explores the spiritual signposts—markers and their marks upon her—in her own life and how it has impacted her patient relations. Whether at the bedside, in her Jewish-Palestinian marriage, in the palm of her son’s hand, in the words she read in the obituary of a surgeon who trained her, she can see the accumulation of these encounters led her to become more spiritually grounded.