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In response to market shifts, manufacturing companies must innovate their production systems to sustain competitiveness. Incremental changes to production systems fail to address these challenges, necessitating radical innovations in manufacturing. This is particularly evident in the pharmaceutical manufacturing industry, where product shortages and an expanding product variety challenge the traditional mass production paradigm. However, there is a noticeable lack of methods and tools to support the initial stages of manufacturing innovation activities in the pharmaceutical and general manufacturing industries. This paper aims to fill this gap by drawing on insights from a radical manufacturing innovation project in a pharmaceutical manufacturing company. Based on the case study findings, six design principles for front-end radical manufacturing innovation processes and potential supporting tools and activities are proposed.

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Design Principles for Front-End Radical Manufacturing Innovation: Insights from Pharmaceutical Manufacturing

  • 会议论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年

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  • Rasmus Andersen,
  • Casper Schou,
  • Ole Madsen,
  • Astrid H. Lassen,
  • Martin B. Jensen,
  • Tristan Schwörer,
  • Bjørn C. Dueholm,
  • Oline V. Olesen

摘要

In response to market shifts, manufacturing companies must innovate their production systems to sustain competitiveness. Incremental changes to production systems fail to address these challenges, necessitating radical innovations in manufacturing. This is particularly evident in the pharmaceutical manufacturing industry, where product shortages and an expanding product variety challenge the traditional mass production paradigm. However, there is a noticeable lack of methods and tools to support the initial stages of manufacturing innovation activities in the pharmaceutical and general manufacturing industries. This paper aims to fill this gap by drawing on insights from a radical manufacturing innovation project in a pharmaceutical manufacturing company. Based on the case study findings, six design principles for front-end radical manufacturing innovation processes and potential supporting tools and activities are proposed.