This article examines modern approaches and application prospects in the field of environmentally friendly pharmacology. The aim of the study is to analyze the technologies, theoretical principles and effective raw material selection methods used to minimize environmental damage during the production of pharmaceutical products. The study, conducted based on a systematic literature review, extensively commented on the issues of biodegradable drug carriers, green chemistry-based synthesis methods, advantages of phytopharmacological components and pharmacoecological risk management. The ecological compatibility of various raw materials was assessed using the E-score model presented in the article, and it was determined that natural substances such as PLA, ginger and propolis have high compatibility. At the same time, the negative effects of synthetic substances (e.g. acetaminophen) on biological circulation and ecosystems were emphasized. As a result, it is recommended to widely apply green technologies, increase recycling capabilities, and accelerate the transition to raw materials of natural origin for the production of sustainable and environmentally friendly pharmaceutical products.