Digital innovation has reshaped entrepreneurship by redefining how ventures are initiated, scaled, and sustained, yet the literature remains fragmented across disciplines. Despite growing interest, there is a lack of comprehensive synthesis mapping the components, key enablers, and conceptual frameworks of digital innovation in entrepreneurship. This study examines the global status of literature development on digital innovation in entrepreneurship. Differentiating itself from previous fragmented studies, this research systematically integrates thematic insights to produce a holistic conceptual model. Employing a Systematic Literature Review (SLR) guided by the PRISMA protocol, 24 peer-reviewed journal articles (2020–2024) from Scopus were analyzed. Components of digital innovation were categorized into seven domains: digital technologies, disruptive business models, user-centric design, data-driven decision-making, agility and experimentation, collaboration and ecosystems, and digital transformation. The key enablers were synthesized using Gioia’s method, resulting in the 4C framework: capability centering, connectivity and collaboration, contextual adaptation, and creative exploration. The study proposed a growing tree conceptual framework illustrating the interconnection between digital components and key enablers. This review concludes that entrepreneurial success in digital contexts relies on technological integration and strategic enabling conditions. The research contributes by offering a unified, cross-disciplinary conceptualization of digital innovation in entrepreneurship, guiding future empirical studies, and informing practitioners on the strategic orchestration of digital capabilities. It highlights the need for micro-, meso-, and macro-level studies to further contextualize digital entrepreneurial ecosystems across diverse global settings.