Syndactyly is one of the most common congenital hand malformations, defined as abnormal interconnection between adjacent digits. Syndactyly can be roughly classified as simple, involving soft tissue only; complex, with distal bone union; and complicated, with more than only distal bone fusion, and this classification has been expanded including nine types and numerous subtypes. Syndactyly can be present in a large variety of forms. Release of syndactyly by classical technique implicates separation of conjoined skin and subcutaneous tissue, preserving integrity of the neurovascular bundles. Techniques for separation of fingers include the digital incisions, commissure reconstruction, and ways to overcome the lack of skin. Separation is carried out via dorsal and volar zigzag incisions (standard or modified) and creating interdigitating flaps. The key area of reconstruction in a syndactyly separation is the creation of the web using a local skin flap. The web in syndactyly can basically be created by a dorsal flap, palmar flap, or a combination of both. For safety reasons two adjacent complete syndactylous fingers are not separated at the same time, as vascular anatomy can be different. There are several treatment options for syndactyly and symbrachydactyly in Poland syndrome, and postoperative care is similar to syndactyly treatment. Separation and correction of the thumb and other fingers in Apert syndrome with as few operations as possible is surgical goal.