Pediatric tumors are highly varied in origin, pathophysiology, and clinical presentation. Benign skin tumors can be divided into tumors of epidermal origin, tumors of dermal origin, and cysts—epidermal and dermal. Benign soft tissue tumors can be divided on the base of the tissue included: benign tumors of fibrous, fat, muscle, neural, and synovial origin. Skin tumors and defects can occur during embryogenesis. These anomalies in head and neck region may have communication with central nervous system. Congenital anomalies at the cervical region are mostly presented as thyroglossal duct cysts and branchial anomalies (sinus, cyst, or fistula). Infective lesions are common in pediatric population. Benign and malignant tumors can be difficult to distinguish in children.