The relationship between Islam and the West has a long history of conflict. Islam often represents the closest “other” and the most active enemy for the so-called West. Religiously, Islam has been the major rival of Christianity since it emerged in the early 600 s CE. After the Iranian Revolution in 1979, US media coverage of Muslims became increasingly negative, which weighted discriminatory attitudes. Khomeini and the hostage crisis provided the United States with a new face and faith to fear. Then, the enduring power of the September 11 (9/11) attacks produced an overwhelming number of Americans experiencing shock, sadness, fear, and anger, resulting in a devastating emotional toll. The rise of anti-Muslim sentiment in the aftermath of 9/11 has had a profound effect on the growing number of Muslims living in the United States. This anti-Muslim sentiment and resulting actions contributed much to an increase in violence and aggression toward institutions and individuals, and the victimization of Muslim women, children, and teens increased multiple-fold. The American Muslim community suffered consequences both at the community and individual levels. In response, many of the advocacy groups, including mental health organizations and institutions, took steps to address these consequences. The fight against Islamophobia is a fight for the psychological and emotional well-being of Muslim Americans.