This chapter presents some polarization imaging techniques that are characterized by sufficient simplicity of instrumental implementation. These techniques can be used both in bench-top studies and in laboratory and clinical conditions for express diagnostics and visualization of pathological changes in the shallow layers of biological tissues. One of the basic principles of the discussed visualization methods is based on the discrimination of co-polarized and cross-polarized components of radiation scattered by the probed medium, taking into account that cross-polarized light is rather associated with multiple scattered radiation penetrating into the medium to a significant depth. Also, to solve problems of express diagnostics and visualization, the effect of optical rotation of the polarization plane and the features of polarization transformation in birefringent media, such as biological tissues with anisotropic structure, can be used.

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Biomedical Diagnostics and Imaging

  • Valery V. Tuchin,
  • Tatiana Novikova,
  • Lihong V. Wang,
  • Dmitry A. Zimnyakov,
  • Hui Ma,
  • Marina V. Alonova,
  • Jiachen Wan

摘要

This chapter presents some polarization imaging techniques that are characterized by sufficient simplicity of instrumental implementation. These techniques can be used both in bench-top studies and in laboratory and clinical conditions for express diagnostics and visualization of pathological changes in the shallow layers of biological tissues. One of the basic principles of the discussed visualization methods is based on the discrimination of co-polarized and cross-polarized components of radiation scattered by the probed medium, taking into account that cross-polarized light is rather associated with multiple scattered radiation penetrating into the medium to a significant depth. Also, to solve problems of express diagnostics and visualization, the effect of optical rotation of the polarization plane and the features of polarization transformation in birefringent media, such as biological tissues with anisotropic structure, can be used.