This article presents a systematic review of global literature on Technology Business Incubation practices in universities, adhering to PRISMA 2020 guidelines. Drawing on 48 peer-reviewed articles published from 2018 to 2024, the review synthesizes conceptual and empirical insights on key aspects of university-based TBIs, including governance models, entrepreneurial support systems, funding mechanisms, business model innovation, performance measurement, and multi-sector collaboration. The research uncovers distinct regional patterns, with Asia focusing on industry linkages, Europe on institutional governance, and North America on financing and acceleration mechanisms. Specialized incubation models such as AI incubators, green technology parks, and living labs were also uncovered, showing practice diversity and flexibility worldwide. The findings have significant implications for Philippine State Universities and Colleges (SUCs) that aim to institutionalize and scale up TBI activities. Recommendations include the establishment of formal incubation units, alignment with DOST and CHED innovation frameworks, and the application of scalable models that are suitable for resource-poor environments. The study is theoretically grounded in the Triple Helix Model and applies elements of Diffusion of Innovation and Business Model Canvas frameworks to position the findings in SUC implementation environments. Limitations include the reliance on English-language sources and the exclusion of grey literature. Future research is recommended to validate global results through case study field research and longitudinal tracking of incubated start-ups in Philippine SUCs.