Regulatory compliance and auditability are crucial for organizational accountability, protection of consumers, and trust amongst industries. This paper provides a comprehensive insight into compliance systems, structures, and audit practices with an emphasis on institutionalizing regulatory requirements into business processes, products, and services. We investigate prominent regulatory frameworks such as the Sarbanes–Oxley Act (SOX), international standards such as ISO 27001 and ITIL, and their enactments in sectors such as finance, healthcare, and pharmaceuticals. The study highlights the role of auditability as a starting point for compliance, enabling verification, validation, and evidence-based monitoring to support organizational openness and stakeholder trust. In addition, we explore elements of compliance management, risk assessment models, audit practices, and supporting roles of internal and external audits. Training and documentation are emphasized as main enablers of the compliance culture, and monitoring and reporting mechanisms and sanctions are reviewed for their capability to improve governance and liability. Trends on the horizon—such as IoT integration, blockchain transparency models, and digitalization—are explored as the most significant drivers of the future of compliance systems. Lastly, the paper argues that real compliance is a combination of regulatory compliance, technological integration, and moral responsibility to ensure that organisations not only conform to the law but also foster lasting trust and resilience.