More than 60 years ago, a breakthrough was reached in the field of international exchange and transport—United Nations adopted and signed a unique legal act in Geneva—the Convention on the Contract for the International Carriage of Goods by Road, also known as the CMR Convention. Until this day, this Convention has been ratified by 58 countries, and it is rightly called the „bible of carriers “. In addition to its main goal of unifying the legal regulation of international road transport of goods and thus facilitating trade and the movement of goods between countries, it created the basis for most of other legal acts, regulating legal relations in freight transportation by road. Although the Convention is a relatively stable legal act, which has been changed only a few times during its period of validity, as the world is rapidly developing and transport with all economic culture is changing, questions arise more and more often in international freight transportation, when the norms of the Convention alone are not sufficient to answer them, we have to turn to national regulations, legal acts and their interaction with this international Convention. Jurisprudence is being developed in solving these problems, and it is this practice in various countries that allows us to take a new, fresh look at this long-standing Convention and its scope of application and adapt it to today’s realities.