Destination trust has become an essential construct in tourism studies, yet its conceptualization, measurement, and implications remain fragmented. This article presents a systematic review of 164 peer-reviewed articles published between 2000 and 2025 and indexed in Scopus and Web of Science. Following PRISMA 2020 guidelines, the analysis combines bibliometric mapping and thematic synthesis to examine how destination trust has been defined, operationalized, and connected to tourist behavior. The results reveal strong convergence around antecedents such as destination image, service quality, perceived risk, authenticity, and electronic word-of-mouth, while consequences are mainly explored through satisfaction, attachment, loyalty, and behavioral intentions like revisiting and recommending. However, the literature still suffers from conceptual dispersion, with some studies adopting a unidimensional approach, others relying on the ABI model, and a few integrating tourism-specific dimensions such as authenticity or conviviality. Methodologically, research remains dominated by quantitative survey-based models, limiting the depth of understanding and neglecting qualitative or mixed methods. In addition, the field shows a marked geographical bias, with most studies concentrated in Asia and Europe. By consolidating fragmented conceptualizations and proposing a refined definition of destination trust that bridges classical trust theory with tourism-specific attributes, this review provides an integrative framework and highlights directions for future research. It also emphasizes the managerial importance of destination trust as a strategic lever for differentiation, competitiveness, and the building of long-term relationships between destinations and tourists.