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This chapter presents an in-depth review of the literature focusing on cognitive health and functional status, including recent research on the growing population of Supercentenarians. Literature on neuropathology and genetic factors indicates that only mild neuropathological alterations were found and centenarians who have healthy brains rely on the maintenance of the perfect balance of genetic variations.

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Literature Review and Theoretical Perspectives

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  • 发表日期：

    2026年

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  • Tanya R. Fitzpatrick

摘要

This chapter presents an in-depth review of the literature focusing on cognitive health and functional status, including recent research on the growing population of Supercentenarians. Literature on neuropathology and genetic factors indicates that only mild neuropathological alterations were found and centenarians who have healthy brains rely on the maintenance of the perfect balance of genetic variations.