In civil engineering, ground vibration is a significant problem, especially in areas with high population density. The use of anti-vibration barriers, particularly metapiles, to reduce vibration propagation has been acknowledged as an efficient engineering vibration attenuation technique because of their many potential uses resulting from their affordability, ease of construction, and adaptability. This work investigates the reduction efficiency of periodic piles using the periodic theory and FEM, through the dynamic reactions of periodic piles in the time domain under seismic and railway vibration. Furthermore, a comprehensive parametric analysis was provided to examine how various geometrical and mechanical characteristics affect the isolation effectiveness of meta piles, where the attenuation effectiveness of periodic piles can be increased by increasing the meta piles' radius, and the soil's Young's modulus. In order to optimize the metapiles in terms of vibrations to be separated, an ANN model was created.