This study aims to assess the impact of roofing sheet color on thermal comfort in residential buildings in Guinea. The research focuses on the effectiveness of white roofs in reducing cooling loads in hot and humid climates. A coupled modeling and experimental approach are implemented to quantify the effect of alternate roof colors on indoor air temperature, surface temperature, discomfort hours, and degree-hours. The results show that white roofs made of high solar reflectance and thermal emittance materials are effective in reducing discomfort hours and degree-hours. The study reveals that the application of white roofs reduces the roof surface temperature by a maximum of 16.5 ℃ compared to the reference red sheet roof and reduces indoor air temperature by a maximum of 1.6 ℃. The study also shows that the reference building composed of roofs with red sheets had 4719 h of discomfort, constituting 54% of the year. The installation of white sheets resulted in 8% reduction in discomfort hours. On the other hand, the use of dark-colored sheets led to a 2% increase in the number of discomfort hours.