East Asian cultural traditions have been influenced by moral principles derived from Confucianism and Buddhism. Additionally, Japan has an indigenous animistic worldview and a deep appreciation for nature, which have intricately shaped its traditional philosophy. These influences foster a cultural ethos that respects the natural order and values things as they are. Japanese tradition emphasizes the spiritual essence of nature and human connections, which in turn impacts decision-making in healthcare. Autonomy is often understood in a relational context, with family consent playing a crucial role in medical decisions. When considering AI and robots from an Asian or specifically Japanese perspective, Japanese culture does not hesitate to attribute personhood or spiritual qualities to these entities. Unlike Western frameworks, which may emphasize strict distinctions between humans and machines, Japan’s cultural background allows for a more fluid interpretation of human-AI interaction. This perspective offers a unique approach to the coexistence of AI, robots, and human society. By integrating traditional Japanese values into discussions on AI ethics, we may develop alternative frameworks that differ from dominant Western paradigms, fostering a more inclusive and diverse understanding of human-technology relations. This analysis suggests that Japan’s cultural and philosophical traditions provide valuable insights into the ethical discourse surrounding AI and robotics, particularly in the context of relational autonomy and human-machine coexistence. Such perspectives may contribute to global discussions on AI governance and its role in society, enriching debates on the ethical, social, and cultural implications of artificial intelligence.