Liver echinococcosis, primarily caused by Echinococcus granulosus, represents the most common form of cystic echinococcosis in humans. Following ingestion of parasite eggs, larvae migrate through the intestinal wall and preferentially localize in the liver, where they develop into hydatid cysts. These cysts can grow slowly and remain asymptomatic for years, or they may cause symptoms such as abdominal pain, hepatomegaly, and jaundice, depending on their size, location, and complications, such as rupture or secondary infection. Diagnosis typically involves abdominal ultrasound (US), computed tomography (CT), or magnetic resonance imaging (MRI), supported by serological assays. Management strategies include surgical resection; percutaneous aspiration, injection of chemicals, and reaspiration (PAIR); and long-term antiparasitic therapy with benzimidazoles. The choice of treatment depends on the cyst type, patient condition, and available resources. The follow-up of patients with echinococcosis is mainly based on imaging techniques, supported by serological tests. Visits, including an imaging examination, should be done every 3–6 months initially and once a year in patients with stable disease.

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Echinococcosis of the Liver

  • Daniela Kniepeiss,
  • Emina Talakić,
  • Peter Schemmer

摘要

Liver echinococcosis, primarily caused by Echinococcus granulosus, represents the most common form of cystic echinococcosis in humans. Following ingestion of parasite eggs, larvae migrate through the intestinal wall and preferentially localize in the liver, where they develop into hydatid cysts. These cysts can grow slowly and remain asymptomatic for years, or they may cause symptoms such as abdominal pain, hepatomegaly, and jaundice, depending on their size, location, and complications, such as rupture or secondary infection. Diagnosis typically involves abdominal ultrasound (US), computed tomography (CT), or magnetic resonance imaging (MRI), supported by serological assays. Management strategies include surgical resection; percutaneous aspiration, injection of chemicals, and reaspiration (PAIR); and long-term antiparasitic therapy with benzimidazoles. The choice of treatment depends on the cyst type, patient condition, and available resources. The follow-up of patients with echinococcosis is mainly based on imaging techniques, supported by serological tests. Visits, including an imaging examination, should be done every 3–6 months initially and once a year in patients with stable disease.