Peach is the second most produced temperate fruit crop in the world following apple. Up to 30% of peaches and nectarines are discarded or lost on-farm in sorting processes, amounting to hundreds of thousands of tons annually of discarded fruit across the sector. Waste streams are also produced during peaches and nectarines processing, including pomace from juicing and stones and wastes produced from peach production, such as orchard pruning. It was selected the following wastes for valorisation the peach pruning wastes. This work includes a comprehensive technical and economic analysis (TEA) for each valorisation route or applied technology. Metrics such as Net Present Value (NPV), Internal Rate of Return (IRR), and payback periods were used to evaluate economic feasibility. From this analysis, it can be concluded that the combustion of pruning wastes indicates a high economic feasibility with excellent financial metrics, including an NPV of €1,774,220, an IRR of 199.67%, and a payback period of less than 1 year. This approach efficiently converts waste into energy, providing a sustainable waste management solution. These valorisation routes, circular economy and bio-refinery approach offer significant contributions to sustainable bio-based operations within the agri-food industry. This approach transforms waste into valuable resources, enhancing both environmental and economic outcomes and contributing to a more sustainable and circular bio-economy.