Sweating is a physiological process that primarily serves the thermoregulation of the human body. However, it can be associated with unpleasant body odor and visible sweat stains, which may negatively impact individuals’ self-confidence. Deodorants and antiperspirants are well-established cosmetic products used for sweat and odor control. This chapter provides an overview of the methodologies employed to evaluate the efficacy of such products. The focus lies on both established and modern assessment techniques, including gravimetric sweat measurements, the Minor test, sensory evaluations, microbiological analyses, the detection of volatile organic compounds (VOCs), and self-assessment tools such as the Hyperhidrosis Disease Severity Scale (HDSS) and the HidroQoL questionnaire. In addition, regulatory requirements (EU, FDA, ISO) and emerging technologies such as wearable sensors and AI-supported data analysis are addressed. The chapter also presents methods for assessing product tolerability, including transepidermal water loss (TEWL), skin pH measurement, and objective evaluation of stratum corneum hydration using biophysical measurement techniques.