This chapter explores the growing body of literature on consumer acceptance of cultured meat, offering a comprehensive overview of the factors that influence acceptance. By synthesizing existing research, the chapter categorizes these factors into three key antecedents: personal, product-related and external factors. Personal factors, such as demographic traits, psychological characteristics and individual awareness, significantly shape consumer perceptions of cultured meat. Product-related factors, including health perceptions, taste expectations and the framing of the product (e.g. labelling and terminology), further impact the willingness of consumers to adopt this innovation. Additionally, external factors—ranging from societal and environmental concerns to trust in the food industry and social influences—play a critical role in determining broader acceptance. The chapter also provides a critical reflection on the limitations of current research on consumer acceptance, highlighting the challenges of relying on intention-based measures and the need for more robust studies that account for actual consumer behaviour. In light of these complexities, businesses in the cultured meat sector are encouraged to take a strategic approach in addressing consumer concerns, actively shaping public perceptions and fostering trust. Practical implications for businesses are discussed, emphasizing the importance of tailored communication strategies and the need to consider consumer expectations and cultural sensitivities when crafting market strategies. The chapter concludes by emphasizing the ongoing need for interdisciplinary research and dialogue to navigate the complexities of consumer acceptance and support the successful market introduction of cultured meat.