With the escalating population the plastic waste generated globally was estimated to about 367 million tons in 2020 and expected to triple by 2060. India witnesses particularly alarming plastic pollution of 9.3 million tons annually accounting for the one-fifth global plastic waste contributor. There is hence an emergent need for waste management strategies. This study explores the conversion of plastic waste into valuable fuels specifically hydrogen gas and diesel through microbial technology, advanced pyrolysis, and catalytic depolymerization technologies. Pyrolysis effectively breaks down different plastic waste at high temperature to produce gas and oil. Diesel produced can be used as fuel for vehicles with existing diesel engines. While hydrogen gas produced will reduce green house emissions if integrated into energy systems like fuel cells or vehicles powered with hydrogen. To optimize plastic degradation microbial enzyme engineering is employed to break down plastics to value-added products like biofuel along with bioreactor optimization for ideal cultivation of microorganisms. With this research it is estimated to produce an approximate of 60:50 percent ratio of hydrogen gas to diesel oil per ton of plastic waste. The research highlights the potential for combining chemical engineering and life science to address plastic pollution. By implementing this we can significantly reduce the landfills while fostering energy production and sustainability. This research underscores to combat pollution and contribute to a greener future.