Cardiac magnetic resonance (CMR) has become a crucial noninvasive imaging modality for evaluating myocardial tissue integrity, function, and pathology. This chapter provides an in-depth overview of CMR techniques, beginning with a foundational understanding of myocardial tissue anatomy and its pathologies, before exploring advanced imaging methods for tissue characterization. CMR allows for the detection of structural abnormalities and tissue alterations, such as fibrosis, edema, scar tissue, and deposits associated with conditions like amyloidosis and sarcoidosis. Key imaging sequences discussed include late gadolinium enhancement (LGE), T1 mapping, T2-weighted imaging and mapping, T2* mapping, and fingerprinting. The chapter emphasizes how these CMR techniques enhance the diagnosis, risk stratification, and treatment monitoring of cardiovascular diseases. LGE imaging, for instance, serves as a gold standard for detecting myocardial fibrosis, while T1 mapping provides quantitative analysis of myocardial tissue, aiding in the assessment of conditions like myocarditis and amyloidosis. T2-weighted imaging and mapping are particularly useful for detecting edema and inflammation, which are crucial in diagnosing myocarditis and distinguishing it from other conditions. The emerging fingerprinting technique, combining multi-parametric mapping in a single scan, offers a comprehensive and efficient approach to tissue characterization. Each technique is examined for its clinical application, from identifying structural changes to guiding patient management and therapeutic decisions. The chapter concludes by highlighting the evolving role of CMR in precision medicine, emphasizing its ability to guide diagnosis, risk stratification, and the monitoring of treatment responses in patients with both ischemic and nonischemic cardiomyopathies.