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Cardiovascular diseases, including ischemic heart disease, remain a significant global health concern, which is still the leading cause of death globally. Ischemia, characterized by inadequate blood supply to the myocardium, can lead to myocardial damage, impaired cardiac function, and ultimately heart failure. Therefore, timely and accurate assessment of myocardial ischemia is crucial. In recent years, advances in medical imaging have paved the way for noninvasive techniques such as CT myocardial perfusion imaging (CT-MPI), enabling quantitative assessment of myocardial ischemia. Several studies showed that CT-MPI has incremental diagnostic value over coronary CTA alone for the identification of hemodynamically relevant coronary artery disease (Nous et al. JACC Cardiovasc Imaging 15:75–87, 2022). This chapter reviews the principles, techniques, and clinical applications of CT-MPI for the assessment of ischemia.

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CT Myocardial Perfusion Imaging

  • 章节

  • 发表日期：

    2026年

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  • Roberto Storelli

摘要

Cardiovascular diseases, including ischemic heart disease, remain a significant global health concern, which is still the leading cause of death globally. Ischemia, characterized by inadequate blood supply to the myocardium, can lead to myocardial damage, impaired cardiac function, and ultimately heart failure. Therefore, timely and accurate assessment of myocardial ischemia is crucial. In recent years, advances in medical imaging have paved the way for noninvasive techniques such as CT myocardial perfusion imaging (CT-MPI), enabling quantitative assessment of myocardial ischemia. Several studies showed that CT-MPI has incremental diagnostic value over coronary CTA alone for the identification of hemodynamically relevant coronary artery disease (Nous et al. JACC Cardiovasc Imaging 15:75–87, 2022). This chapter reviews the principles, techniques, and clinical applications of CT-MPI for the assessment of ischemia.