Transcatheter interventions are increasingly used in the management of structural heart diseases in patients with high-risk factors for surgery. Echocardiography is the first-line imaging modality used for pre-procedural assessment. Computed tomography (CT) is an indispensable imaging modality in pre-procedural assessment for transcatheter interventions, often providing complementary information to echocardiography. CT provides crucial information including evaluation of contraindications, accurate measurements for device sizing, and assessment of several key parameters necessary for a successful procedure. Magnetic resonance imaging (MRI) isn typically used when CT cannot be performed for some reason. In this chapter, the utility of quantitative CT and MRI imaging in pre-procedural assessment of common transcatheter interventions for structural heart diseases is reviewed.