The building sector accounts for over one-third of global energy consumption and approximately 26% of energy-related CO2 emissions. Renovating existing buildings to improve their energy performance is a key strategy for lowering operational energy demand and achieving global climate targets. In this context, accurate energy simulations are essential, enabling reliable evaluation and optimization of new products and solutions. This study is conducted within the EU-funded EASI ZERo project, which aims to develop easy-to-install building envelope components for energy-efficient renovations, targeting near-zero energy balance and minimal CO2 emissions. The components under development integrate bio-sourced insulation, low-carbon paints and plasters, and lightweight frames for windows and doors. As part of the project, a dedicated laboratory facility was modelled using both IDA ICE and EnergyPlus to evaluate a novel wall component (test wall). The simulation results are validated against measurements collected over a 16-day period, including operative temperature, surface temperatures, and heat fluxes through the test wall. The results demonstrate good overall agreement between simulations and measurements. EnergyPlus showed better performance than IDA ICE in predicting operative temperature (Normalized Root Mean Square Error, NRMSE: 0.25 versus 0.32), glazing surface temperature (NRMSE: 0.06 versus 0.08), and heat flux (NRMSE: 0.16 versus 0.18); whereas IDA ICE provided slightly better predictions for the test wall surface temperature (NRMSE: 0.116 versus 0.119). This study provides valuable guidance for selecting appropriate simulation tools and contributes to enhancing the accuracy of thermal performance predictions, which is crucial for optimizing energy use in renovation projects and supporting sustainability goals.