Calcification of cardiovascular stent and graft is a common complication that can result in secondary surgery to replace the failing stent. SulfurSulfur functional groups prepared through low temperatureLow temperature plasma were used to prevent biomineralizationBiomineralization of polymerPolymer materials commonly used to make vascular grafts. The results indicate that these polymersPolymer naturally biomineralize in body like conditions, where FTIR and XPS showed carbonate and phosphate functional groups of the untreated polymersPolymer. Plasma treatment using ethyl vinyl sulfone showed significant decrease of these same functional groups. Microscopy of the polymeric samples showed stark contrast between the treated and untreated samples due to decrease in biomineralizationBiomineralization of calcium phosphate. After biomimetic treatment of sulfur plasmas on polymersPolymer and control, it was observed that the low temperatureLow temperature plasmas caused a decrease of biomineralizationBiomineralization on treated samples.