The Blue Economy offers a sustainable framework for harnessing ocean resources to drive economic growth, enhance livelihoods, and preserve marine ecosystems. This chapter examines how digital technologies—artificial intelligence (AI), data analytics, and blockchain—transform decision-making within this paradigm. Applications in marine resource management, predictive modeling, and transparent governance are discussed, with the El Niño–Southern Oscillation (ENSO) dataset serving as a case study to demonstrate data-driven insights for fisheries, aquaculture, and climate resilience. AI and analytics facilitate real-time monitoring and forecasting, while blockchain ensures traceability and compliance. Opportunities such as efficiency gains and increased stakeholder trust are highlighted alongside challenges like data gaps and infrastructure requirements. Through integration of these technologies, alignment with the United Nations’ Sustainable Development Goals—particularly SDG 14 (Life Below Water)—can be achieved, fostering a resilient, equitable, and sustainable future for ocean-dependent communities.