The combination of calcium phosphates (CaPs), suchAdditive Manufacturing (AM) as hydroxyapatite (HA), with polylactic acid (PLA) represents an effective strategy for the development of compositeComposites biomaterialsBiomaterials with applications in bone tissue engineering. While CaPs provide bioactivity and osteoconductivity, PLA offers good mechanical propertiesMechanical properties and processability. This synergy facilitates the fabrication of customized scaffolds by additive manufacturingAdditive Manufacturing (AM). In this context, HA was synthesized from eggshells and biogenic sulfuric acid, proposing a sustainable and low-cost way to obtain bioactiveBioactive materials. The HA-PLA blends were processed by extrusion and characterized morphologically (using SEM) and mechanically. Strength, stiffness, and deformation properties were evaluated, and it was observed that the incorporation of HA significantly modified the mechanical behavior of PLA, suggesting an improvement in the bioactivity of the material without compromising its processability. These results demonstrate the potential of HA-PLA compositeComposites for applications in tissue engineering, especially in the fabrication of personal bone structures.

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Production of HA-PLA Filaments for Additive Manufacturing from Hydroxyapatite of Biogenic Origin

  • Sandra Milena Restrepo Arcila,
  • Santiago Erazo,
  • Marco Antonio Márquez Godoy,
  • Henry Alonso Colorado Lopera

摘要

The combination of calcium phosphates (CaPs), suchAdditive Manufacturing (AM) as hydroxyapatite (HA), with polylactic acid (PLA) represents an effective strategy for the development of compositeComposites biomaterialsBiomaterials with applications in bone tissue engineering. While CaPs provide bioactivity and osteoconductivity, PLA offers good mechanical propertiesMechanical properties and processability. This synergy facilitates the fabrication of customized scaffolds by additive manufacturingAdditive Manufacturing (AM). In this context, HA was synthesized from eggshells and biogenic sulfuric acid, proposing a sustainable and low-cost way to obtain bioactiveBioactive materials. The HA-PLA blends were processed by extrusion and characterized morphologically (using SEM) and mechanically. Strength, stiffness, and deformation properties were evaluated, and it was observed that the incorporation of HA significantly modified the mechanical behavior of PLA, suggesting an improvement in the bioactivity of the material without compromising its processability. These results demonstrate the potential of HA-PLA compositeComposites for applications in tissue engineering, especially in the fabrication of personal bone structures.