MATLAB® (short for MATrix LABoratory) is a programming and numerical computing platform created specifically for engineers and scientists. It is used to analyze and design the systems and products that are transforming our world. This chapter provides a practical introduction to MATLAB, focusing on its application in solving mathematical problems. It covers core essentials including environment navigation, variable definition, and the creation and manipulation of matrices and vectors. Special emphasis is placed on the Symbolic Math Toolbox, demonstrating how to define symbolic variables to perform algebraic manipulations, differentiation, and integration. Additionally, the text explores data visualization.