This study is a journey to identify the opportunities, challenges, and future research scope in the metaverse entrepreneurship based on a systematic literature review. The Scopus database is employed for the selection of documents. For review, 25 documents are selected through the Scientific Procedures and Rationales for Systematic Literature Reviews (SPAR-4-SLR) protocol. The study identified the opportunities in metaverse entrepreneurship connected with the technological enablers of entrepreneurship, innovative business and market opportunities, transformation of education and entrepreneurial learning, economic growth and social inclusion, and further development in metaverse entrepreneurship. The major challenges of the metaverse in entrepreneurship encompass economic, technological, regulatory, security, and skill-based aspects. Metaverse entrepreneurship is a galaxy waiting to be explored. This study represents the first attempt to synthesize the existing research through a systematic literature review methodology. To policymakers, this study provides guidance for the creation of a regulatory framework across social, economic, and legal dimensions. To entrepreneurs, this study helps to identify opportunities in metaverse entrepreneurship not just as a marketplace but as an ocean for innovation and ideation. To educators, this study is a light into the rethinking and redesigning of the curriculum and the pedagogical approach to integrating metaverse tools and entrepreneurship education to create a generation with immense knowledge in digital entrepreneurship. The limitation of this in-depth study is, it only included the documents from the Scopus database till August 2025. The novelty of the study is to the theory by informing future research possibilities in this evolving domain by highlighting current research trends.