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A practical comparative analysis of two workflow management systems is presented: the Galaxy cloud platform and cwltool—a reference Common Workflow Language implementation. Using high-speed imaging of droplet dynamics as a benchmark application, we demonstrate that while both platforms successfully process large-scale image datasets (thousands of frames per experiment), they differ significantly in nonfunctional properties critical for platform selection. The Galaxy platform provides an integrated cloud-based collaborative environment with resource management and visual workflow composition, while cwltool demonstrates superior computational efficiency (2x faster average processing time) on identical hardware configuration.

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Processing of High-Speed Imaging Data with Galaxy and Cwltool

  • 会议论文

  • 发表日期：

    2026年

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  • Ilya Baranov,
  • Maxim Gorodnichev,
  • Sergey Starinskiy,
  • Nikolay Miskiv,
  • Elena Starinskaya

摘要

A practical comparative analysis of two workflow management systems is presented: the Galaxy cloud platform and cwltool—a reference Common Workflow Language implementation. Using high-speed imaging of droplet dynamics as a benchmark application, we demonstrate that while both platforms successfully process large-scale image datasets (thousands of frames per experiment), they differ significantly in nonfunctional properties critical for platform selection. The Galaxy platform provides an integrated cloud-based collaborative environment with resource management and visual workflow composition, while cwltool demonstrates superior computational efficiency (2x faster average processing time) on identical hardware configuration.