Supply Chain Planning in agri-food supply chains faces increasing challenges due to global disruptions and resource constraints. Supply Chain 5.0, driven by human-centered approaches, enhances resilience and sustainability by aligning dynamic demand strategies with technological advancements in uncertain environments. To address these complexities, this study applies the Best-Worst Method (BWM) to prioritize key strategic criteria across four dimensions, enabling consistent and structured decision-making. The results emphasize the relevance of advanced supply chain planning and human-centered innovation in fostering adaptive resilience and shaping a more sustainable supply chain. These findings support the transition toward resilient, sustainable, and human-driven agri-food supply chains aligned with the Supply Chain 5.0 framework.