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The present study attempted to enhance the mechanical properties and antibacterial effectiveness of dental PMMA materials. This was achieved by incorporating zinc oxide and copper oxide nanoparticles into a PMMA resin matrix, through the thermal curing method. The resulting composites were analyzed using various techniques such as transmission electron microscopy, scanning electron microscopy, and energy dispersive spectroscopy to examine their chemical composition, microstructure, and morphology. Additionally, the flexural properties and antibacterial effectiveness of the PMMA/ZnO-NPs composite were assessed. The results showed that the uniform distribution of nanoparticles in the matrix significantly improved the flexural properties of the PMMA biopolymer, especially with the addition of 2 wt% CuO nanoparticles. The separate addition of 2% ZnO-NPs and 2% CuO-NPs led to an increase in flexural modulus by 51.3% and 96%, respectively. In addition, the maximum flexural strengths increased by 32.9% and 60% respectively. Additionally, the study revealed that the PMMA/NPs composite exhibited remarkable antimicrobial properties against the Gram-positive bacterial strain Staphylococcus aureus ATCC 29213. The absence of bacterial growth on the developed composite indicated the bactericidal effect of the samples. These findings demonstrate that the mechanical limitations of traditional dental prosthetic materials can be overcome with this nanocomposite, offering more effective and durable solutions in prosthodontics.

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Enhanced Antibacterial and Mechanical Properties of PMMA-Based Dental Materials via Nanoparticles Incorporation

  • 会议论文

  • 发表日期：

    2026年

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  • Chokri Ben Aissa,
  • Najoua Barhoumi,
  • Kaouther Khlifi,
  • Ines Karkouch,
  • Wiem Bousslama

摘要

The present study attempted to enhance the mechanical properties and antibacterial effectiveness of dental PMMA materials. This was achieved by incorporating zinc oxide and copper oxide nanoparticles into a PMMA resin matrix, through the thermal curing method. The resulting composites were analyzed using various techniques such as transmission electron microscopy, scanning electron microscopy, and energy dispersive spectroscopy to examine their chemical composition, microstructure, and morphology. Additionally, the flexural properties and antibacterial effectiveness of the PMMA/ZnO-NPs composite were assessed. The results showed that the uniform distribution of nanoparticles in the matrix significantly improved the flexural properties of the PMMA biopolymer, especially with the addition of 2 wt% CuO nanoparticles. The separate addition of 2% ZnO-NPs and 2% CuO-NPs led to an increase in flexural modulus by 51.3% and 96%, respectively. In addition, the maximum flexural strengths increased by 32.9% and 60% respectively. Additionally, the study revealed that the PMMA/NPs composite exhibited remarkable antimicrobial properties against the Gram-positive bacterial strain Staphylococcus aureus ATCC 29213. The absence of bacterial growth on the developed composite indicated the bactericidal effect of the samples. These findings demonstrate that the mechanical limitations of traditional dental prosthetic materials can be overcome with this nanocomposite, offering more effective and durable solutions in prosthodontics.