This paper presents a systematic review of the existing literature on the role of User Interface (UI) design in software usability and its influence on User Experience (UX). A total of 20 peer-reviewed articles published between 2018 and 2024 were analyzed and selected from reputable online databases. The review employed qualitative content analysis to extract usability metrics and design principles related to user interaction. The findings consistently showed that well-designed UI/UX significantly enhances user interaction, usability, and overall software performance. Key usability attributes identified include ease of navigation, visual clarity, logical layout, and accessibility. Interfaces that are intuitive and free of ambiguity lead to higher user satisfaction and improved task completion rates. Moreover, the study emphasizes that user-centered design strategies and iterative usability testing are essential for developing functional and engaging applications. The research suggests tailoring UI elements to user behaviors and emotional responses contributes to more personalized and effective software experiences. These insights provide a valuable foundation for future UI/UX development frameworks that enhance software usability across different user groups and platforms.