Working equids serve essential roles for human development in worldwide agricultural production and transport service together with labor-intensive production fields worldwide. This segment summarizes the worldwide numbers of working equids combined with their multiple functions and healthcare obstacles as well as trade and breeding patterns. The work animals play an essential economic role since mechanization is difficult to implement in certain regions thus advancing both local earnings and sustainable growth. The chapter explores the controversial donkey skin trade which produces significant consequences on worldwide donkey populations together with their welfare oversight and sociological stability. This analysis demonstrates the importance of donkeys and mules and hinnies through detailed evaluation so the chapter asks for increased welfare standards with sustainable management and policy changes that uphold their evolving and historical value. This discussion uses historical and present-day perspectives to create a more comprehensive understanding of rarely studied animals and to demonstrate why worldwide collaboration remains essential for their future preservation and well-being.